Biochem/physiol Actions
Diallyl trisulfide inactivates Akt to trigger mitochondrial translocation of BAD and caspase-mediated apoptosis in human prostate cancer cells. Diallyl trisulfide-induced apoptosis in human prostate cancer cells involves c-Jun N-terminal kinase and extracellular-signal regulated kinase-mediated phosphorylation of Bcl-2
General description
Diallyl trisulfide, a constituent of garlic and onions, is a proapoptotic compound that also posesses antioxidant activity.
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