Sulfaphenazole, >=98%

Code: S0758-1G D2-231

Application

Sulfaphenazole has been used as a positive control to inhibit cytochrome P450 2C9 (cyp2c9) to quantify Rhodiola rosea inhibition. It has also been used a...


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Your Price
€368.53 1G
€453.29 inc. VAT

Application

Sulfaphenazole has been used as a positive control to inhibit cytochrome P450 2C9 (cyp2c9) to quantify Rhodiola rosea inhibition. It has also been used as cytochrome P450 2C9 (cyp2c9) inhibitor in endothelial cells and microsomal preparations.

Biochem/physiol Actions

Antibacterial. Specific inhibitor of CYP2C9. Blocks pro-inflammatory and atherogenic effects of linoleic acid (increase in oxidative stress and activation of AP-1) mediated by CYP2C9. Specific inhibitor of CYP2C9. Blocks pro-inflammatory and atherogenic effects of linoleic acid (increase in oxidative stress and activation of AP-1) mediated by CYP2C9. Inhibits bradykinin-induced tPA release.

Packaging

1 g in poly bottle

assay≥98%
formpowder
Gene Informationhuman ... CYP2C18(1562), CYP2C19(1557), CYP2C9(1559)
InChI keyQWCJHSGMANYXCW-UHFFFAOYSA-N
InChI1S/C15H14N4O2S/c16-12-6-8-14(9-7-12)22(20,21)18-15-10-11-17-19(15)13-4-2-1-3-5-13/h1-11,18H,16H2
Quality Level100
SMILES stringNc1ccc(cc1)S(=O)(=O)Nc2ccnn2-c3ccccc3
solubilityethanol: 25 mg/mL, clear, colorless to yellow
storage temp.2-8°C
Cas Number526-08-9
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