CYPEXPRESS(TM) CONTROL

Application

Poster: A Novel, Robust Recombinant Human P450 Biocatalytic SystemPoster: Evaluation of Dry Powder Preparations of Permeabilized Pichia pastoris Cells Expressing Human Cytochrome P450 2D6 Enzyme (CYP2D6) for Drug Metabolite GenerationPoster: Facile Scale-up Biocatalytic Production of P-450 Metabolites Using a Novel Recombinant Human Catalytic SystemPoster: Multi-Cycle Production of Metabolites with human P450 systemsPoster: Rapid identifcation and production of metabolites using CypExpress^™ 2D6m 3A4 and 2C9Poster: Rapid identifcation and production of metabolites using stabilized dried powder (SDP) of human cytochrome P450S (hCYPS) 2D6, 3A4, and 2C9 engineered in yeastPoster: Utilizing a Novel Biocatalytic Human P450 System for the Multi - Cycle Production of Metabolites

Biochem/physiol Actions

Cytochrome P450 is a heterogeneous family of isozymes whose primary function is to oxidize small molecules, both as a function of intermediary metabolism (e.g., fatty acids) and to detoxify exogenous compounds (drugs or toxins). Some isoforms have narrow substrate specificity, while others are promiscuous.

Features and Benefits

CypExpress^™ Control is a permeabilized and stabilized dried yeast powder preparation using an empty vector and processed identically to CypExpress^™ P450 products.

Legal Information

6538 is a trademark of American Type Culture Collection

CypExpress is a trademark of Oxford Biomedical Research

Physical form

Light yellow, very fine powder

Reconstitution

Per Protocol/Variable