Carnosol,

Code: C9617-5MG D2-231

Application

Carnosol has been used as an anti-cancer agent:to test its anti-cancer and anti-proliferative activities on cancer stem-like cells (CSCs) and Glioblastoma multifo...


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Your Price
€379.00 5MG
€466.17 inc. VAT

Application

Carnosol has been used as an anti-cancer agent:to test its anti-cancer and anti-proliferative activities on cancer stem-like cells (CSCs) and Glioblastoma multiforme (GBM) cellsto inspect its anti-carcinogenic effects on nineteen genes involved in up-and down-regulation of different genetic carcinogenesis pathways and on HeLa cells in human cervical cancer modelas a reference standard to identify and quantify the metabolites of rosemary extract using liquid chromatography coupled to tandem mass spectrometry (LC/ESI-MS/MS)

Biochem/physiol Actions

Carnosol together with carnosic acid (CA) accounts for 90% of the antioxidant activity of rosemary leaves. It exerts neuroprotective properties and protects against neuroinflammation, and oxidative stress-induced brain damage under chronic stress conditions. Carnosol is a strong chemo-therapeutic agent studied for several types of cancer like breast, leukemia, skin, prostate, and colon. It is also an antimicrobial agent.

A phenolic diterpene with antioxidant and anticarcinogenic activities.

General description

Carnosol (CAR) is an ortho-diphenolic diterpene, extracted from the Mediterranean dietary herb Rosmarinus officinalisL. (rosemary). It was first isolated from the Salvia carnosa (Sage) plant. Carnosol is also a pro-electrophilic molecule.

Packaging

5 mg in glass bottle

biological sourceRosemarinus officinalis L.
formpowder
InChI keyXUSYGBPHQBWGAD-PJSUUKDQSA-N
InChI1S/C20H26O4/c1-10(2)11-8-12-13-9-14-19(3,4)6-5-7-20(14,18(23)24-13)15(12)17(22)16(11)21/h8,10,13-14,21-22H,5-7,9H2,1-4H3/t13-,14-,20+/m0/s1
Quality Level200
shipped indry ice
SMILES stringCC(C)c1cc2[C@@H]3C[C@H]4C(C)(C)CCC[C@]4(C(=O)O3)c2c(O)c1O
storage temp.−20°C
Cas Number5957-80-2
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