Analysis Note

ControlRat lung tissue lysate

Application

Research CategoryInflammation & Immunology

Anti-SLAMF2 (CD48 Antibody) is a highly specific rabbit polyclonal antibody, that targets CD48 & has been tested in western blotting.

Research Sub CategoryInflammation & Autoimmune Mechanisms

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

General description

The signaling lymphocyte-activation molecule family member 2 (SLAMF2), also known as CD48, is a GPI-anchored protein that exists as both a soluble and membrane-associated form and is expressed in almost all leukocyte populations particularly in mitogen-stimulated human lymphocytes. SLAMF2 is a high-affinity ligand for SLAMF4, also known as 2B4, as well as a low-affinity ligand for CD2, and can thus can stimulate cells expressing these receptors. It has been shown to be an IL-3-induced activating receptor on eosinophils and is likely to be involved in promoting allergic inflammation. SLAMF2 is also thought to be involved in the IL-18/IL-18R signaling cascade in T and natural killer cells to produce interferon-gamma.

Immunogen

KLH-conjugated linear peptide corresponding to human SLAMF2.

Other Notes

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

Physical form

Antigen Affinity Purified

Purified rabbit polyclonal in buffer containing PBS with up to 0.1% sodium azide.

Quality

Evaluated by Western Blotting in rat lung tissue lysate.

Western Blotting Analysis: 2 µg/mL of this antibody detected SLAMF2 in 15 µg of rat lung tissue lysate.

Storage and Stability

Stable for 1 year at 2-8°C from date of receipt.

Target description

~17 and ~28 kDa observed