Aurothioglucose hydrate, >=97% (titration)

Code: A0606-5MG D2-231

Application

Aurothioglucose hydrate has been used in redox stress survival assay in human cell lines and for inducing obese phenotype in mice.

Biochem/physiol A...


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€200.83 5MG
€247.02 inc. VAT
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Application

Aurothioglucose hydrate has been used in redox stress survival assay in human cell lines and for inducing obese phenotype in mice.

Biochem/physiol Actions

Aurothioglucose, a gold compound used clinically to treat rheumatoid arthritis, has recently been found to be a potent PKCiota-Par6 interaction inhibitor, with an IC50 approximately 1 µM. Disruption of this interaction disrupts a rac1 signaling pathway that is required for transformed growth in non-small-cell lung cancer.

Features and Benefits

This compound is featured on the PKC page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

Packaging

5, 25 mg in glass bottle

assay≥96% (titration)
colorwhite to beige
formpowder
InChI keySGVIEHTYEMEDRR-PKXGBZFFSA-M
InChI1S/C6H12O5S.Au.H2O/c7-1-2-3(8)4(9)5(10)6(12)11-2;;/h2-10,12H,1H2;;1H2/q;+1;/p-1/t2-,3-,4+,5-,6-;;/m1../s1
Quality Level100
SMILES stringO.OC[C@H]1O[C@H](S[Au])[C@H](O)[C@@H](O)[C@@H]1O
solubilityH2O: 5 mg/mL, clear
storage conditiondesiccated
storage temp.2-8°C
Cas Number12192-57-3
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