Application

Used for chemical probe synthesis, this trifunctional building block contains a light-activated benzophenone, alkyne tag, and bromine synthetic handle. When appended to a ligand or pharmacophore through its brominated linker, this building block allows for UV light-induced covalent modification of a biological target with potential for downstream applications via the alkyne tag. Use alone or in parallel with other multi-functional building blocks to discover the optimal probe for your chemical biology experiments.

Other Notes

Technology Spotlight: Trifuctional Probe Building BlocksDevelopment of Sulfonamide Photoaffinity Inhibitors for Probing Cellular γ-SecretaseA library approach to rapidly discover photoaffinity probes of the mRNA decapping scavenger enzyme DcpS

Packaging

100 mg in glass bottle