02:0 SM (D18:1/2:0)

Application

02:0 SM (d18:1/2:0) is suitable for use in liposomes to measure ostreolysin A (OlyA) binding in order to infer the effects of phosphatidylcholines (PCs) on sphingomyelin (SM)/cholesterol interactions.

Biochem/physiol Actions

Sphingomyelin (SM) has high cholesterol affinity, which aids localization and interactions of proteins. It functions as a precursor to ceramides and other sphingolipid metabolites.

General description

Sphingomyelin is abundantly present in the cell membranes, particularly in myelin sheath and red blood cells. It has a ceramide unit with a phosphorylcholine moiety linked to position 1.

Packaging

5 mL Clear Glass Sealed Ampule (860580P-5mg)