Application
Glucosyl(β) Sphingosine (d18:1) or D-glucosyl-β1-1′-D-erythro-sphingosine may be used: to screen lipids that rapidly and reversibly altertransepithelialelectrical resistance (TER) or tight junction (TJ) permeability in epithelial tissue as a standard for the quantification of glucosyl sphingosinein Gaucher patients using liquid chromatography electrospray ionization tandem mass spectrometric (LC/ESI-MS/MS) as an internal standard for the quantification of lysoglucosylceramide in plasma for Gaucher disease using liquid chromatography with tandem mass spectrometry (LC-MS/MS)
Biochem/physiol Actions
Glucosylsphingosine is a potential biomarker for Gaucher′sdisease.It modulatesCa2+releasein the brainmicrosomes.
General description
Glucosylsphingosine is a lyso derivative of glucosylceramide (GlcCer).
Packaging
5 mL Amber Glass Screw Cap Vial (860535P-5mg)
5 mL Amber Glass Screw Cap Vial (860535P-50mg)
5 mL Amber Glass Screw Cap Vial (860535P-25mg)
This product has met the following criteria to qualify for the following awards: