SAFINGOL

Code: 860488P-5MG D2-231

Application

Safingol has been used as a substituent of dihydrosphingosine (dhSph) to increase the cytotoxic response in N-(4-hydroxyphenyl)retinamide (4-HPR)-resista...


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€319.88 5MG
€393.45 inc. VAT
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Application

Safingol has been used as a substituent of dihydrosphingosine (dhSph) to increase the cytotoxic response in N-(4-hydroxyphenyl)retinamide (4-HPR)-resistant cells.

General description

Safingol is a synthetic L-threo-stereoisomer of endogenous (D-erythro-) sphinganine. It acts as an inhibitor of protein kinase C and sphingosine kinase in vitro. Safingol is involved in ceramide generation and induction of apoptosis. It is known to stimulate antitumor activity of cisplatin.

Packaging

5 mL Amber Glass Screw Cap Vial (860488P-5mg)

formpowder
InChI keyOTKJDMGTUTTYMP-UHFFFAOYSA-N
InChI1S/C18H39NO2/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-18(21)17(19)16-20/h17-18,20-21H,2-16,19H2,1H3
manufacturer/tradenameAvanti Polar Lipids 860488P
packagingpkg of 1 × 5 mg (860488P-5mg)
shipped indry ice
SMILES stringCCCCCCCCCCCCCCC[C@@](O)([H])[C@@]([H])(N)CO
storage temp.−20°C
Cas Number15639-50-6
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