C18:0 GM3 (SYNTHETIC)

Code: 860074W-100UG D2-231

Biochem/physiol Actions

Ganglioside monosialodihexosylganglioside (GM3) modulates apoptosis, cell proliferation and differentiation. It is also essential for cellular signali...


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Biochem/physiol Actions

Ganglioside monosialodihexosylganglioside (GM3) modulates apoptosis, cell proliferation and differentiation. It is also essential for cellular signaling pathways, cell adhesion and mobility. GM3 prevents the action of fibroblast growth factor receptor. Low levels of gangliosideGM3 is associated with the pathogenesis ofrheumatoid arthritis. GM3 maintainsimmunologicalfunctions by inhibiting cytokine production.

General description

Ganglioside monosialodihexosylganglioside (GM3) are membrane-bound glycosphingolipids (GSLs). It comprisesasialic acid residueand an oligosaccharide head structure. GM3 is present in milk and kidney cells. GM3is the most widely present ganglioside in tissues.

Packaging

2 mL Amber Glass Sealed Ampule (860074W-100ug)

assay>99% (TLC)
concentration0.1 mg/mL (860074W-100ug)
formmethanol solution
manufacturer/tradenameAvanti Polar Lipids 860074W
packagingpkg of 1 × 1 mL (860074W-100ug)
shipped indry ice
SMILES string[H][C@](/C=C/CCCCCCCCCCCCC)(O)[C@@]([H])(NC(CCCCCCCCCCCCCCCCC)=O)CO[C@H]1[C@H](O)[C@@H](O)[C@H](O[C@@H]2O[C@H](CO)[C@@H]([C@H](O[C@@]3(C([O-])=O)O[C@@H]([C@H](O)[C@H](O)CO)[C@@](NC(C)=O)([H])[C@@H](O)C3)[C@H]2O)O)[C@@H](CO)O1.[NH4+]
storage temp.−20°C
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