Biochem/physiol Actions
IG7 is potent in enhancing Fas ligand (FasL) induced apoptosis in colon carcinoma cells SW480 and RKO. IG7 enhances FasL mediated phosphorylation of p38 and janus kinase (JNK). IG7 enhances nuclear factor-kappa B (NF-κB) activation by FasL. IG7 exhibits low toxicity.
General description
IG7 is a ceramide analog.
Packaging
5ML Glass Amber Screw Cap Vial (857410P-1MG)
5ML Glass Amber Screw Cap Vial (857410P-5MG)
This product has met the following criteria to qualify for the following awards: