2-CHLORO-22-DIFLUOROACETOPHENONE

Code: 792373-10G D2-231

Application

2-Chloro-2,2-difluoroacetophenone can be used:As a reagent in the difluoromethylation of various phenols to yield aryl difluoromethyl ethers.As a precursor in the...


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€311.60 10G
€383.27 inc. VAT

Application

2-Chloro-2,2-difluoroacetophenone can be used:As a reagent in the difluoromethylation of various phenols to yield aryl difluoromethyl ethers.As a precursor in the Baylis-Hillman reaction of fluoroalkyl ketones to obtain chlorodifluoromethyl containing products.As a substrate in the synthesis of propargyl alcohols using a novel ruthenium catalyst.

Reagent is an effective product for the synthesis of difluoromethylated phenols in the presence of mild base and aqueous solvent.

General description

2-Chloro-2,2-difluoroacetophenone is a difluorocarbene reagent, which is generally used in the synthesis of 2,2-difluoro enol silyl ethers, and gem-difluoromethene derived compounds.

Packaging

1, 10 g in glass bottle

assay95%
bp94-96 °C/35 mmHg (lit.)
density1.3178 g/mL at 25 °C, 1.293 g/mL at 25 °C (lit.)
formliquid
InChI keyMNOONJNILVDLSW-UHFFFAOYSA-N
InChI1S/C8H5ClF2O/c9-8(10,11)7(12)6-4-2-1-3-5-6/h1-5H
Quality Level100
refractive indexn20/D 1.497 (lit.), n20/D 1.4954
SMILES stringFC(F)(Cl)C(=O)c1ccccc1
Cas Number384-67-8
This product has met the following criteria to qualify for the following awards:



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