Ryanodine; High Purity

Biochem/physiol Actions

Cell permeable: no

Primary TargetCa2+ transport and action in muscle

Reversible: no

Product does not compete with ATP.

General description

Naturally occurring alkaloid that blocks the release of Ca²⁺ from the sarcoplasmic reticulum. Has many complex effects on Ca²⁺ transport and action in muscle. Purified from Ryanodine Mixture.

Naturally occurring alkaloid that blocks the release of Ca²⁺ from the sarcoplasmic reticulum. Has many complex effects on Ca²⁺ transport and action in muscle.

Legal Information

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Other Notes

Sorrentino, V., and Volpe, P. 1993. Trends Pharmacol. Sci.14, 98.Sabbadini, R., et al. 1992. J. Biol. Chem.267, 15475.Feher, J.J., and Lipford, G.B. 1985. Biochim. Biophys. Acta813, 77.Marban, E., and Wier, W.G. 1985. Circ. Res.56, 133.Sukto, J.L., et al. 1985. Fed. Proc.44, 2984.

Packaging

500 µg in Plastic ampoule

Reconstitution

Following reconstitution, refrigerate (4°C). Stock solutions are stable for up to 1 month at 4°C.

Warning

Toxicity: Harmful (C)