Biochem/physiol Actions

Secondary TargetPKCα, PKCβ

Primary TargetPKC

General description

The PKC Inhibitor Set controls the biological activity of PKC. This small molecule/inhibitor is primarily used for Phosphorylation & Dephosphorylation applications.

Inhibition of protein kinase C (PKC) is one of the most direct methods for investigating its role in cellular metabolism and tumorigenesis. Calbiochem^® brand is pleased to offer a convenient set of PKC inhibitors for your research needs. Supplied with a data sheet.

Contains 250 µg of Bisindolylmaleimide I (Cat. No. 203290), 50 µg of Calphostin C, Cladosporium cladosporioides (Cat. No. 208725), 5 mg of Chelerythrine Chloride (Cat. No. 220285), 500 µg of Gö 6976 (Cat. No. 365250), 500 µg of Myristoylated Protein Kinase C Inhibitor 20-28, Cell-Permeable (Cat. No. 476480), and 1 mg of Ro-32-0432 (Cat. No. 557525). Supplied with a data sheet.

Legal Information

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Other Notes

Eicholtz, T., et al. 1993. J. Biol. Chem.268, 1982.Kleinschroth, J., et al. 1993. Bioorg. Med. Chem. Lett.3, 1959.Martiny-Baron, G.M., et al. 1993. J. Biol. Chem.268, 9194.Ward, N.E., and O′Brian, C.A. 1993. Biochemistry32, 11903.Wilkinson, S.E., et al. 1993. Biochem. J.294, 335.Barg, J., et al. 1992. J. Neurochem.59, 1145.Gopalakrishna, R., et al. 1992. FEBS Lett.314, 149.Bruns, R.F., et al. 1991. Biochem. Biophys. Res. Commun.176, 288.Toullec, D., et al. 1991. J. Biol. Chem.266, 15771.Herbert, J.M., et al. 1990. Biochem. Biophys. Res. Commun.1172, 993.Tamaoki, T., et al. 1990. Biotechnology8, 732.Kobayashi, E., et al. 1989. Biochem. Biophys. Res. Commun.159, 548.

Packaging

1 set in Glass bottle

Reconstitution

Following reconstitution, aliquot and freeze -20°C.

Warning

Toxicity: Multiple Toxicity Values, refer to MSDS (O)