Serine/Threonine Kinase Inhibitor Set

Biochem/physiol Actions

Secondary TargetPKC, MLCK, Cam kinase II, PKG

Cell permeable: yes

Primary TargetPKA

General description

A convenient set that offers several highly selective serine/threonine kinase inhibitors. Kinases play an important role in numerous signaling cascades. Highly selective protein kinase inhibitors are useful for dissecting these cascades to determine which specific kinases are involved in producing particular biological effects. The Serine/Threonine Kinase Inhibitor Set contains the following highly selective serine/ threonine kinase inhibitors in one convenient set: r>r> Bisindolylmaleimide I (Cat. No. 203290), 250 µgr> H-89, Dihydrochloride (Cat. No. 371963), 1 mgr> KN-93 (Cat. No. 422708), 1 mgr> ML-7 (Cat. No. 475880), 1 mgr> Protein Kinase G Inhibitor (Cat. No. 370654), 1 mgr> Staurosporine (Cat. No. 569397), 100 µg

Legal Information

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Other Notes

Martiny, G., et al. 1993. J. Biol. Chem.268, 9194.Toullec, D., et al. 1991. J. Biol. Chem.266, 15771.Chijiwa, T., et al. 1990. J. Biol. Chem.265, 5267.Simu, M., et al. 1991. Biochem. Biophys. Res. Commun.181, 968.Saitoh, M., et al. J. Biol. Chem.262, 7796.Glass, D.B., et al. 1983. Biochem. J.213, 159.Seynaeve, C.M., et al. 1994. Mol. Pharmacol.45, 1207.Meyer, T., et al. 1989. Int. J. Cancer43, 851.

Packaging

1 set in Glass bottle

Reconstitution

Following reconstitution, aliquot and freeze (-20°C). Stock solutions of each inhibitor are stable for up to 3 months at -20°C.

Warning

Toxicity: Multiple Toxicity Values, refer to MSDS (O)