Biochem/physiol Actions

Primary TargetNMDA receptors

General description

A very potent, water-soluble antagonist of the NMDA receptors complex acting at the strychnine-insensitive glycine binding site (K_i = 79 nM vs. [3H]-glycine).

Legal Information

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Other Notes

Baron, B., et al. 1991. Eur. J. Pharmacol.206, 149.Baron, B., et al. 1990. Mol. Pharmacol.38, 554.Mugnaini, M., et al. 1998. J. Recept. Signal Transduct. Res.18, 91.

Packaging

10 mg in Glass bottle

Reconstitution

Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.

Warning

Toxicity: Standard Handling (A)