MG Nitric Oxide Synthase; Neuro 1PC x 5M

Biochem/physiol Actions

Reversible: no

Product does not compete with ATP.

Primary TargetnNOS

Cell permeable: yes

Target K_i: 120 nM against nNOS

General description

A cell-permeable, potent, and highly selective inhibitor of neuronal nitric oxide synthase (nNOS) (K_i = 120 nM). Displays >2,500-fold and 192-fold selectivity over eNOS and iNOS, respectively.

A cell-permeable, potent and highly selective inhibitor of neuronal nitric oxide synthase (nNOS); (K_i = 120 nM). Displays >2500-fold and 320-fold selectivity over eNOS and iNOS, respectively.

Legal Information

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Other Notes

Hah, J.M., et al. 2001. J. Med. Chem.44, 2667.

Packaging

Packaged under inert gas

5 mg in Plastic ampoule

Physical form

Supplied as a dihydrate.

Reconstitution

Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.

Warning

Toxicity: Standard Handling (A)