Dipeptidylpeptidase IV Inhibitor IV; K579

Code: 317642-5MG D2-231

General description

A cyanopyrrolidine compound that acts as a potent DPP IV inhibitor (IC50 = 3, 5, 8, and 8 nM in inhibiting rat, human, monkey, and canine DDP I...


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€203.93 EACH
€250.83 inc. VAT

General description

A cyanopyrrolidine compound that acts as a potent DPP IV inhibitor (IC50 = 3, 5, 8, and 8 nM in inhibiting rat, human, monkey, and canine DDP IV, respectively). Oral administration of K579 in rats in vivo has been shown to reduce blood DPP IV activity and augment GLP-1 and insulin response after glucose intake and significantly reduce plasma glucose concentration.

Please note: 328.4 is the anhydrous molecular weight; please refer to the vial label for the lot-specific hydration and molecular weight.

Legal Information

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Other Notes

Takasaki, K., et al. 2004. Eur. J. Pharmacol.505, 237.Takasaki, K., et al. 2004. Eur. J. Pharmacol.486, 335.Takasaki, K., et al. 2004. J. Pharmacol. Sci.95, 291.

Please note: 328.4 is the anhydrous molecular weight; please refer to the vial label for the lot-specific hydration and molecular weight.

Packaging

5 mg in Glass bottle

Packaged under inert gas

Warning

Toxicity: Standard Handling (A)

assay≥97% (HPLC)
colorlight brown
formsolid
manufacturer/tradenameCalbiochem®
Quality Level100
shipped inambient
solubilityDMSO: 32 mg/mL, 1 M HCl: 16 mg/mL, ethanol: 6.5 mg/mL
storage conditionprotect from light, OK to freeze
storage temp.2-8°C
Cas Number440100-64-1
This product has met the following criteria to qualify for the following awards:



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