Choline chloride, BioUltra, >=99.0% (AT)

Code: 26978-100G D2-231

Biochem/physiol Actions

The enzymatic activities of butyrylcholinesterase (BChE) and paraoxonase 1 (PON1), two serum enzymes synthesized by the liver and related with inflamm...


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Biochem/physiol Actions

The enzymatic activities of butyrylcholinesterase (BChE) and paraoxonase 1 (PON1), two serum enzymes synthesized by the liver and related with inflammation, were decreased in a sepsis animal model injected with LPS. Choline chloride administered intravenously at 20 mg/kg body weight prevents the LPS-mediated decreases in the activities of these two enzymes .

Choline is an essential nutrient, commonly grouped with the B complex vitamins, that plays key roles in many biological processes.

Other Notes

Restores cholinergic, biochemical and pharmacological activities in striata of decorticated rats

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Substrates

Choline acetyltransferase substrate

λ1 M in H2O
anion tracessulfate (SO42-): ≤50 mg/kg
assay≥99.0% (AT)
biological sourcesynthetic
cation tracesBi: ≤5 mg/kg, Na: ≤50 mg/kg, Mo: ≤5 mg/kg, Al: ≤5 mg/kg, K: ≤50 mg/kg, Li: ≤5 mg/kg, Cr: ≤5 mg/kg, Mn: ≤5 mg/kg, Sr: ≤5 mg/kg, Mg: ≤5 mg/kg, Ca: ≤10 mg/kg, Pb: ≤5 mg/kg, Cu: ≤5 mg/kg, Ba: ≤5 mg/kg, Fe: ≤5 mg/kg, Zn: ≤5 mg/kg, Ni: ≤5 mg/kg, Cd: ≤5 mg/kg, Co: ≤5 mg/kg
colorcolorless to white
formpowder or crystals
impuritiesinsoluble matter, passes filter test
InChI keySGMZJAMFUVOLNK-UHFFFAOYSA-M
InChI1S/C5H14NO.ClH/c1-6(2,3)4-5-7;/h7H,4-5H2,1-3H3;1H/q+1;/p-1
mp302-305 °C (dec.) (lit.)
pH5.0-7.5 (25 °C, 1 M in H2O)
product lineBioUltra
Quality Level200
SMILES string[Cl-].C[N+](C)(C)CCO
solubilityH2O: 1 M, clear, colorless
UV absorptionλ: 260 nm Amax: 0.015, λ: 280 nm Amax: 0.010
Cas Number67-48-1
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