Application

vascular function, tissue engineering, pharmacology of vascular tissue

Cell Line Origin

Artery

Components

Smooth Muscle Cell Basal Medium containing 10% FBS & 10% DMSO

General description

HUASMC has been used to study effects of snake venom on smooth muscle cells (Mora, 2008); secretion mechanism of the (pro)renin receptor (Yoshikawa, 2011) and the role of proteasomes (Martin, 2014) in the development of cardiovascular diseases; and to develop novel material surfaces to inhibit smooth muscle cell proliferation at the same time allowing endothelial cells adhesion and proliferation in order to reduce risk associated with vascular implants (Kanie, 2012). Characterization: positive for smooth muscle cell specific alpha-actin expression.

Preparation Note

2nd passage, >500,000 cells in Smooth Muscle Cell Basal Medium containing 10% FBS & 10% DMSO Can be cultured at least 16 doublings

Subculture Routine

Please refer to the HUASMC Culture Protocol.