General description

BCL6 is a transcriptional regulator gene that codes for a 706-amino-acid nuclear zinc finger protein. In normal tissue, anti-BCL6 antibody shows strong nuclear staining in a subset of B-lymphocytes, mostly located in germinal centers (GC). BCL6 expression is usually present in follicular lymphomas, diffuse large B-cell lymphomas, and Burkitt lymphomas.

Legal Information

Cell Marque is a trademark of Sigma-Aldrich Co. LLC

Linkage

BCL6 Positive Control Slides, Product No. 227S, are available for immunohistochemistry (formalin-fixed, paraffin-embedded sections).

Other Notes

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Physical form

Solution in Tris Buffer, pH 7.3-7.7, with 1% BSA and ﹤0.1% Sodium Azide

Preparation Note

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Quality