Biochem/physiol Actions

Primary Targetcaspase-6

Reversible: yes

Product does not compete with ATP.

Cell permeable: yes

General description

A potent, cell-permeable, and reversible inhibitor of caspase-6.The N-terminal sequence (amino acids 1-16) corresponds to the hydrophobic region of the signal peptide of Kaposi fibroblast growth factor and confers cell permeability to the peptide.

Potent, cell-permeable and reversible inhibitor of caspase-6.

Legal Information

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Other Notes

Hirata, H., et al. 1998. J. Exp. Med. 187, 587.Thornberry, N.A., and Lazebnik, Y. 1998. Science 281, 1312.

Packaging

1 mg in Plastic ampoule

Reconstitution

Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.

Sequence

Ac-Ala-Ala-Val-Ala-Leu-Leu-Pro-Ala-Val-Leu-Leu-Ala-Leu-Leu-Ala-Pro-Val-Glu-Ile-Asp-CHO

Warning

Toxicity: Standard Handling (A)