General description

CD31, or platelet/endothelial cell adhesion molecule-1 (PECAM-1), is a vascular cell adhesionand signaling molecule that plays a role in maintaining the vascular permeability barrierat endothelial cell junctions. Immunohistochemical detection of CD31 shows cytoplasmicand membranous expression in non-neoplastic and neoplastic vascular endothelial cells,including neoplasms of vascular origin such as hemangiomas and angiosarcomas.

Legal Information

Cell Marque is a trademark of Sigma-Aldrich Co. LLC

Linkage

CD31 Positive Control Slides, Product No. 131S, are available for immunohistochemistry (formalin-fixed, paraffin-embedded sections).

Other Notes

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Physical form

Solution in Tris Buffer, pH 7.3-7.7, with 1% BSA and ﹤0.1% Sodium Azide

Preparation Note

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