YN1

Code: SML0947-10MG D2-231

Biochem/physiol Actions

YN1 is a potent inhibitor of PFKFB3 (6-Phosphfructo-2-kinase/fructose-2,6-bisphosphatase: IC50 = 670 nM). PFKFB3 is over expressed in many ...


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€94.80 10MG
€116.60 inc. VAT
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Biochem/physiol Actions

YN1 is a potent inhibitor of PFKFB3 (6-Phosphfructo-2-kinase/fructose-2,6-bisphosphatase: IC50 = 670 nM). PFKFB3 is over expressed in many cancers, and catalyzes the production of fructose-2,6-bisphosphate, which can potentiate PFK1 activity, enhancing glycolysis in tumor cells. YN1 inhibits glycolysis and proliferation in HeLa cells.

Packaging

10, 50 mg in glass bottle

assay≥98% (HPLC)
colorwhite to beige
formpowder
InChI keyBMZFZTMWBCFKSS-UHFFFAOYSA-N
InChI1S/C15H10O5/c16-9-3-1-8(2-4-9)11-7-20-15-10(13(11)18)5-6-12(17)14(15)19/h1-7,16-17,19H
Quality Level100
solubilityDMSO: 10 mg/mL, clear
storage conditiondesiccated
storage temp.2-8°C
Cas Number75187-63-2
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