XEN445

Code: SML1324-25MG D2-231

Biochem/physiol Actions

XEN445 is a potent and selective inhibitor of endothelial lipase with an IC50 of 237 nM and high selectivity over hepatic and lipoprotein l...


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€362.40 25MG
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Biochem/physiol Actions

XEN445 is a potent and selective inhibitor of endothelial lipase with an IC50 of 237 nM and high selectivity over hepatic and lipoprotein lipases. In experiments with wild-type mice, XEN445 raised plasma HDL-cholesterol levels by 16% after 3 days and by 30% after 9 days dosing.

Packaging

5, 25 mg in glass bottle

assay≥98% (HPLC)
colorwhite to beige
formpowder
Quality Level100
solubilityDMSO: 10 mg/mL, clear
storage temp.2-8°C
Cas Number1515856-92-4
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