Wedelolactone

Code: PHL89823-10MG D2-231

Biochem/physiol Actions

Wedelolactone inhibits NF-κB-mediated gene transcription in cells by blocking the phosphorylation and degradation of IκBα. Irreversible...


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€535.10 10MG
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Biochem/physiol Actions

Wedelolactone inhibits NF-κB-mediated gene transcription in cells by blocking the phosphorylation and degradation of IκBα. Irreversible inhibitor of IKKα and β kinase activity (IC50 ﹤ 10 µM). Wedelolactone has no effects on p38 MAP kinase or Akt.

General description

This substance is a primary reference substance with assigned absolute purity (considering chromatographic purity, water, residual solvents, inorganic impurities). The exact value can be found on the certificate. Produced by PhytoLab GmbH & Co. KG

Legal Information

phyproof is a registered trademark of PhytoLab GmbH & Co. KG

assay≥90.0% (HPLC)
formsolid
gradeprimary reference standard
InChI keyXQDCKJKKMFWXGB-UHFFFAOYSA-N
InChI1S/C16H10O7/c1-21-6-2-10(19)14-12(3-6)23-16(20)13-7-4-8(17)9(18)5-11(7)22-15(13)14/h2-5,17-19H,1H3
manufacturer/tradenamePhytoLab
product linephyproof® Reference Substance
SMILES stringCOc1cc(O)c-2c(OC(=O)c3c-2oc4cc(O)c(O)cc34)c1
storage temp.2-8°C
Cas Number524-12-9
This product has met the following criteria to qualify for the following awards:



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