UVI3003

Code: SML1950-25MG D2-231

Biochem/physiol Actions

UVI3003 is a high-affinity selective Pan-retinoid X receptor (RXR) full antagonist. Retinoid actions are predominantly mediated through the formation ...


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€512.50 25MG
€630.38 inc. VAT
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Biochem/physiol Actions

UVI3003 is a high-affinity selective Pan-retinoid X receptor (RXR) full antagonist. Retinoid actions are predominantly mediated through the formation of various RAR and RXR isotype heterodimers that can act as either transcriptional repressors or activators. UVI3003 has been used as a tool to test the contribution of RXR to transactivation by a given RXR heterodimer. It was found to induce teratogenesis in zebrafish embryos and recently was found to inhibit A?42 aggregation.

assay≥98% (HPLC)
colorwhite to beige
formpowder
Quality Level100
SMILES stringCC(CCC1(C)C)(C)C2=C1C=C(C3=C(O)C=CC(C=CC(O)=O)=C3)C(OCCCCC)=C2
solubilityDMSO: 20 mg/mL, clear
storage temp.−20°C
Cas Number847239-17-2
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