TC-2153

Code: SML1299-25MG D2-231

Biochem/physiol Actions

TC-2153 is a potent inhibitor of STEP (STriatal-Enriched protein tyrosine Phosphatase) that forms a reversible covalent bond with the catalytic cystei...


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€452.40 25MG
€556.45 inc. VAT
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Biochem/physiol Actions

TC-2153 is a potent inhibitor of STEP (STriatal-Enriched protein tyrosine Phosphatase) that forms a reversible covalent bond with the catalytic cysteine in STEP. TC-2153 increases tyrosine phosphorylation of STEP substrates ERK1/2, Pyk2, and GluN2B in cell cultures. TC-2153 improves cognitive function in transgenic AD mice.

Packaging

5, 25 mg in glass bottle

assay≥95% (HPLC)
colorwhite to beige
formpowder
Quality Level100
shipped inwet ice
solubilityDMSO: 5 mg/mL, clear
storage temp.−20°C
Cas Number1381769-23-8
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