Biochem/physiol Actions

Primary TargetDela opioid receptor

General description

A very potent and selective δ opioid receptor agonist (IC₅₀ = 0.32 µM). Shown to induce dose- and time-dependent antinociception after i.c.v., i.th. and i.p. administration in mice. Widely used in studies of depression and inflammatory injuries. It is also reported to be acted upon heteromeric u-d receptors.

Legal Information

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Other Notes

Pradhan, A., et al., 2013. Mol Pain.9, 8.Saitoh, A., et al., 2012. Curr. Neuropharmacol.10, 231.Metcalf. M. et al. 2012. ACS Chem. Neurosci.3, 505.Bilsky, J., et al. 1995. J. Pharmacol. Exp. Ther.273, 359.

Packaging

10 mg in Glass bottle

Reconstitution

Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.

Warning

Toxicity: Standard Handling (A)