SBC-115076

Code: SML1712-5MG D2-231

Biochem/physiol Actions

SBC-115076 is an inhibitor of PCSK9 (proprotein convertase subtilisin-kexin 9). PCSK9 binds to the LDL receptor, preventing it from removing LDL chole...


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€175.00 5MG
€215.25 inc. VAT
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OVERVIEW

Biochem/physiol Actions

SBC-115076 is an inhibitor of PCSK9 (proprotein convertase subtilisin-kexin 9). PCSK9 binds to the LDL receptor, preventing it from removing LDL cholesterol from the blood. SBC-115076 was shown to inihbit PCSK9, blocking LDLR degradation in HEK293T cells expressing PCSK9 and to increase the uptake of LDL by liver cells in vitro. SBC-115076 lowered cholesterol levels in mice fed a high fat diet.

Packaging

5, 25 mg in glass bottle

SPECIFICATIONS
assay≥98% (HPLC)
colorwhite to beige
formpowder
Quality Level100
SMILES stringCC1=CC(C(C(C(C2=CC=NC=C2)N3CCCN4CCOCC4)=C(O)C3=O)=O)=CC=C1OCC5=CC=CC=C5
solubilityDMSO: 20 mg/mL, clear
storage temp.−20°C
DOCUMENTS
RANGE
ATTRIBUTES
Cas Number489415-96-5
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