RANIRESTAT

Code: SML1315-5MG D2-231

Biochem/physiol Actions

Ranirestat (AS-3201) is an aldose reductase (AR) inhibitor. Aldose reductase is a rate-limiting enzyme in the conversion of D-glucose to fructose via ...


read more

Your Price
€266.10 5MG
€327.30 inc. VAT
REQUEST

Biochem/physiol Actions

Ranirestat (AS-3201) is an aldose reductase (AR) inhibitor. Aldose reductase is a rate-limiting enzyme in the conversion of D-glucose to fructose via D-sorbitol. Ranirestat has been implicated in diabetic complications (cataract formation, retinopathy, neuropathy, nephropathy). Ranirestat prevents sorbitol accumulation and is thus hoped to be effective in the remedy of diabetic neuropathy.

Packaging

5, 25 mg in glass bottle

assay≥97% (HPLC)
colorwhite to beige
formpowder
InChI keyQCVNMNYRNIMDKV-QGZVFWFLSA-N
InChI1S/C17H11BrFN3O4/c18-10-4-3-9(11(19)6-10)8-21-14(24)12-2-1-5-22(12)17(16(21)26)7-13(23)20-15(17)25/h1-6H,7-8H2,(H,20,23,25)/t17-/m1/s1
optical activity[α]/D -5 to -10°, c = 1.0 in methanol
Quality Level100
SMILES stringO=C(N1CC2=C(F)C=C(Br)C=C2)C3=CC=CN3[C@@]4(CC(NC4=O)=O)C1=O
solubilityDMSO: 20 mg/mL, clear
storage temp.−20°C
Cas Number147254-64-6
This product has met the following criteria to qualify for the following awards:



PROCEED TO CHECKOUT

HAVE AN ACCOUNT? LOGIN

GUEST CHECKOUT

Proceed as a guest. You will have the option to register to access exclusive pricing and stock availability features after checkout.