RANIRESTAT

Code: SML1315-5MG D2-231

Biochem/physiol Actions

Ranirestat (AS-3201) is an aldose reductase (AR) inhibitor. Aldose reductase is a rate-limiting enzyme in the conversion of D-glucose to fructose via ...


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€266.10 5MG
€327.30 inc. VAT
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OVERVIEW

Biochem/physiol Actions

Ranirestat (AS-3201) is an aldose reductase (AR) inhibitor. Aldose reductase is a rate-limiting enzyme in the conversion of D-glucose to fructose via D-sorbitol. Ranirestat has been implicated in diabetic complications (cataract formation, retinopathy, neuropathy, nephropathy). Ranirestat prevents sorbitol accumulation and is thus hoped to be effective in the remedy of diabetic neuropathy.

Packaging

5, 25 mg in glass bottle

SPECIFICATIONS
assay≥97% (HPLC)
colorwhite to beige
formpowder
InChI keyQCVNMNYRNIMDKV-QGZVFWFLSA-N
InChI1S/C17H11BrFN3O4/c18-10-4-3-9(11(19)6-10)8-21-14(24)12-2-1-5-22(12)17(16(21)26)7-13(23)20-15(17)25/h1-6H,7-8H2,(H,20,23,25)/t17-/m1/s1
optical activity[α]/D -5 to -10°, c = 1.0 in methanol
Quality Level100
SMILES stringO=C(N1CC2=C(F)C=C(Br)C=C2)C3=CC=CN3[C@@]4(CC(NC4=O)=O)C1=O
solubilityDMSO: 20 mg/mL, clear
storage temp.−20°C
DOCUMENTS
RANGE
ATTRIBUTES
Cas Number147254-64-6
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