R-7050

Code: SML1377-25MG D2-231

Biochem/physiol Actions

R-7050 is a cell-permeable TNF-α receptor antagonist that blocks TNF-α-induced binding of TNF-αRI with TNFαR-associated death doma...


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€369.60 25MG
€454.61 inc. VAT
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Biochem/physiol Actions

R-7050 is a cell-permeable TNF-α receptor antagonist that blocks TNF-α-induced binding of TNF-αRI with TNFαR-associated death domain protein and receptor interacting protein 1, blocking internalization of the TNFα-TNFαR complex. R-7050 was found to reduce neurovascular injury in a mouse model of hemorrhagic stroke.

Packaging

5, 25 mg in glass bottle

assay≥95% (HPLC)
colorwhite to beige
formpowder
InChI keySUUMKHOVGVYGOP-UHFFFAOYSA-N
InChI1S/C16H8ClF3N4S/c17-9-6-7-11-12(8-9)24-13(22-23-15(24)16(18,19)20)14(21-11)25-10-4-2-1-3-5-10/h1-8H
Quality Level100
shipped inwet ice
SMILES stringClC1=CC=C(N=C(SC2=CC=CC=C2)C3=NN=C(C(F)(F)F)N34)C4=C1
solubilityDMSO: 2 mg/mL, clear (warmed)
storage temp.−20°C
Cas Number303997-35-5
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