PYZD-4409

Code: SML1188-5MG D2-231

Biochem/physiol Actions

PYZD-4409 inhibts ATP-dependent activation of human ubiquitin activating enzyme E1 with an IC50 of 20 mM. PYZD-4409 induces cell death, and...


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€108.70 5MG
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Biochem/physiol Actions

PYZD-4409 inhibts ATP-dependent activation of human ubiquitin activating enzyme E1 with an IC50 of 20 mM. PYZD-4409 induces cell death, and inhbits clonogenic growth of leukemia and myeloma cell lines, and inhibits leukemia xenograft tumor growth in mice.

Packaging

5, 25 mg in glass bottle

assay≥98% (HPLC)
color, white to very dark brown
formpowder
InChI keyMSYMKEYWUWVZQY-UHFFFAOYSA-N
InChI1S/C14H7ClFN3O5/c15-10-5-7(1-3-11(10)16)18-14(21)9(13(20)17-18)6-8-2-4-12(24-8)19(22)23/h1-6H,(H,17,20)
Quality Level100
SMILES stringFC1=CC=C(N2C(C(C(N2)=O)=CC3=CC=C([N+]([O-])=O)O3)=O)C=C1Cl
solubilityDMSO: 10 mg/mL, clear
storage temp.−20°C
Cas Number423148-78-1
Hazard Class6.1
Un Number2811
Pack GroupIII
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