PQ-10

Code: SML1116-25MG D2-231

Biochem/physiol Actions

PQ-10 (6,7-dimethoxy-4-[3-(quinoxalin-2-yloxy)pyrrolidin-1-yl]quinazoline), is capable of suppressing tumor cell growth. It can also reverse the RO-4-...


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€342.70 25MG
€421.52 inc. VAT
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OVERVIEW

Biochem/physiol Actions

PQ-10 (6,7-dimethoxy-4-[3-(quinoxalin-2-yloxy)pyrrolidin-1-yl]quinazoline), is capable of suppressing tumor cell growth. It can also reverse the RO-4-1284-induced sedation and catalepsy.

PQ-10 is a potent and selective inhibitor of phosphodiesterase 10A (PDE10). Apparently, PQ-10 enhances basic auditory information processing in rats. PQ-10 as other PED10 inhibitors suppresses a growth of human non-small cell lung cancer (NSCLC) cell lines.

Features and Benefits

This compound is a featured product for Cyclic Nucleotide research. Click here to discover more featured Cyclic Nucleotide products. Learn more about bioactive small molecules for other areas of research at sigma.com/discover-bsm.

Packaging

5, 25 mg in glass bottle

SPECIFICATIONS
assay≥98% (HPLC)
colorwhite to beige
formpowder
InChI keyUBIIFKJMNRPNMT-CQSZACIVSA-N
InChI1S/C22H21N5O3/c1-28-19-9-15-18(10-20(19)29-2)24-13-25-22(15)27-8-7-14(12-27)30-21-11-23-16-5-3-4-6-17(16)26-21/h3-6,9-11,13-14H,7-8,12H2,1-2H3/t14-/m1/s1
Quality Level100
SMILES stringCOC1=CC2=C(N3C[C@H](OC4=CN=C(C=CC=C5)C5=N4)CC3)N=CN=C2C=C1OC
solubilityDMSO: 10 mg/mL, clear
storage temp.2-8°C
DOCUMENTS
RANGE
ATTRIBUTES
Cas Number927691-21-2
This product has met the following criteria to qualify for the following awards:



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