Biochem/physiol Actions

PMA (polymethacrylate) forms nanodiscs spontaneously by fragmentation or solubilization of the lipid bilayers. It is used in designing of nanodisc-forming polymer to mimic the amphiphilic nature of proteins and peptides. PMA N−C4−60−4.7 efficiently solubilised the lipid membrane and forms lipid nanodiscs with 1,2-dimyristoyl-sn-glycero-3-phosphocholine (DMPC). The addition of PMA N−C4−60−4.7 lowered the light scattering intensity of Escherichia coli suspension.

General description

PMA (polymethacrylate) random copolymer is amphiphilic and consists of hydrophobic and hydrophilic sidechains.

Packaging

5mL glass amber screw cap vial (880134P-100mg)

20mL clear glass screw cap vial (880134P-500mg)