Biochem/physiol Actions

Primary Targetα7 nAChR

General description

A potent agonist highly selective for α7 nicotinic acetylcholine receptor (α7 nAChR). Bioavaible admitted orally. Widely used in studies of the functional roles of α7 nAChR in learning and memory, sensory gating, and cognitive functions as well as Schizophrenia and Alzheimer′s disease.

Legal Information

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Other Notes

Mazurov, A., et al., 2011. J. Med. Chem.54, 7943.Wishka, G., et al., 2006. J. Med. Chem.49, 4425.Faghih, R., et al., 2008. J. Med. Chem.51, 701.

Reconstitution

Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.

Warning

Toxicity: Standard Handling (A)