NSC130813

Code: SML0922-25MG D2-231

Biochem/physiol Actions

NSC130813 blocks protein-protein interactions between XPF and ERCC1, two proteins involved in nucleotide excision repair (NER). The compound, NSC13081...


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€416.20 25MG
€511.93 inc. VAT
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Biochem/physiol Actions

NSC130813 blocks protein-protein interactions between XPF and ERCC1, two proteins involved in nucleotide excision repair (NER). The compound, NSC130813, blocks repair of DNA damage induced by platinum-based ctyotoxic drugs and DNA alkylating agents. NSC130813 synergistically potentiates cell death in cancer cell lines treated with cisplatin or mitomycin C.

Other Notes

air sensitive

Packaging

5, 25 mg in glass bottle

assay≥98% (HPLC)
coloryellow to orange
formpowder
Quality Level100
solubilityH2O: 10 mg/mL, clear
storage temp.−20°C
Cas Number1082532-95-3
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