MUBRITINIB

Code: SML1312-25MG D2-231

Biochem/physiol Actions

Mubritinib (TAK-165) is a potent and selective inhibitor of the human epidermal growth factor receptor 2 ErbB (HER2) tyrosine kinase. Mubritinib poten...


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€288.90 25MG
€355.35 inc. VAT
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Biochem/physiol Actions

Mubritinib (TAK-165) is a potent and selective inhibitor of the human epidermal growth factor receptor 2 ErbB (HER2) tyrosine kinase. Mubritinib potently inhibits proliferation of cancer cell lines over- expressing ErbB2.

Packaging

5, 25 mg in glass bottle

assay≥98% (HPLC)
colorwhite to beige
formpowder
Gene Informationhuman ... ERBB2(2064)
InChI keyZTFBIUXIQYRUNT-MDWZMJQESA-N
InChI1S/C25H23F3N4O2/c26-25(27,28)21-9-4-20(5-10-21)8-13-24-30-22(18-34-24)17-33-23-11-6-19(7-12-23)3-1-2-15-32-16-14-29-31-32/h4-14,16,18H,1-3,15,17H2/b13-8+
Quality Level100
SMILES stringFC(F)(F)C1=CC=C(/C=C/C2=NC(COC3=CC=C(C=C3)CCCCN4C=CN=N4)=CO2)C=C1
solubilityDMSO: 5 mg/mL, clear (warmed)
storage temp.2-8°C
Cas Number366017-09-6
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