MSP-3

Code: SML1623-5MG D2-231

Biochem/physiol Actions

MSP-3 is a Transient Receptor Potential Vanilloid Type-1 (TRPV1) channel agonist with antioxidant and neuroprotective activity. MSP-3 activated TRPV1 ...


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Biochem/physiol Actions

MSP-3 is a Transient Receptor Potential Vanilloid Type-1 (TRPV1) channel agonist with antioxidant and neuroprotective activity. MSP-3 activated TRPV1 channels with similar efficacy as compared to capsaicin (EC50 = 870 nM). It protected a keratinocyte cell line from oxidative stress damage with more efficacy than capsaicin and prevented the damage caused by H2O2 in differentiated human neuroblastoma cell lines as well as in rat cortical slices.

assay≥98% (HPLC)
colorwhite to beige
formoil
InChI keyHCUVEUVIUAJXRB-UHFFFAOYSA-N
InChI1S/C16H19NO3S/c1-20-15-10-12(7-8-14(15)18)11-17-16(19)6-2-4-13-5-3-9-21-13/h3,5,7-10,18H,2,4,6,11H2,1H3,(H,17,19)
Quality Level100
SMILES stringO=C(NCC1=CC=C(O)C(OC)=C1)CCCC2=CC=CS2
storage temp.room temp
Cas Number1820968-63-5
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