MS37452

Code: SML1405-25MG D2-231

Biochem/physiol Actions

MS37452 is a selective Chromobox homolog 7 (CBX7) modulator that disrupts CBX7ChD binding to H3K27me3. MS37452 inhibits CBX7 binding to INK4/ARF gene ...


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€691.60 25MG
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Biochem/physiol Actions

MS37452 is a selective Chromobox homolog 7 (CBX7) modulator that disrupts CBX7ChD binding to H3K27me3. MS37452 inhibits CBX7 binding to INK4/ARF gene locus, and induces decline of p14/ARF and p16/INK4a in human PC3 cells.

Packaging

5, 25 mg in glass bottle

assay≥98% (HPLC)
colorwhite to beige
formpowder
InChI keyLUMCNRKHZRYQOV-UHFFFAOYSA-N
InChI1S/C22H26N2O5/c1-16-6-4-7-17(14-16)29-15-20(25)23-10-12-24(13-11-23)22(26)18-8-5-9-19(27-2)21(18)28-3/h4-9,14H,10-13,15H2,1-3H3
Quality Level100
shipped inwet ice
SMILES stringO=C(COC1=CC(C)=CC=C1)N2CCN(C(C3=CC=CC(OC)=C3OC)=O)CC2
solubilityDMSO: 20 mg/mL, clear
storage conditiondesiccated
storage temp.−20°C
Cas Number423748-02-1
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