MONNA

Code: SML0902-25MG D2-231

Biochem/physiol Actions

MONNA is a TMEM16A (ANO1) calcium-activated chloride channel blocker. MONNA blocks rhTMEM16A (ANO1) channel currents in HEK293 cells with and IC5...


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€503.20 25MG
€618.94 inc. VAT
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OVERVIEW

Biochem/physiol Actions

MONNA is a TMEM16A (ANO1) calcium-activated chloride channel blocker. MONNA blocks rhTMEM16A (ANO1) channel currents in HEK293 cells with and IC50 of 1.27 µM. The compound MONNA does not affect related human or mouse chloride channels bestrophin-1, CLC2 and CFTR at concentrations up to 10 µM.

MONNA (benzbromarone (Benzb) and N-((4-methoxy)-2-naphthyl)-5-nitroanthranilic acid) is a TMEM16A antagonists. It affects the liberation of sarcoplasmic reticulum (SR) calcium in human airway smooth muscle cells.

Packaging

5, 25 mg in glass bottle

SPECIFICATIONS
assay≥98% (HPLC)
colorlight orange to dark orange
formpowder
Quality Level100
solubilityDMSO: 20 mg/mL, clear
storage temp.2-8°C
RANGE
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