Biochem/physiol Actions
Cell permeable: no
Reversible: no
Target IC50: 15 µM inhibiting iron-dependent peroxidation in rat brain homogenates
Product does not compete with ATP.
Primary TargetA free radical scavenger and antioxidant
General description
A free radical scavenger and antioxidant that reduces post-ischemie brain injury. Inhibits iron-dependent peroxidation in rat brain homogenates (IC50 = 15 µM). Inhibits mitochondrial permeability transition pore.
A free radical scavenger and antioxidant that reduces post-ischemic brain injury. Inhibits iron-dependent peroxidation in rat brain homogenates (IC50 = 15 µM). Inhibits mitochondrial permeability transition pore.
Legal Information
CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany
Other Notes
Katare, R. G., et al. 2003. Am. J. Physiol.285, H2171.Kawai, H., et al. 1997. J. Pharmacol. Exp. Ther. 281, 921.Yamamoto, Y., et al. 1996. Redox. Report 2, 333.Watanabe, T., et al. 1994. J. Pharmacol. Exp. Ther. 268, 1597.Nishi, H., et al. 1989. Stroke 20, 1236.
Packaging
Packaged under inert gas
500 mg in Plastic ampoule
Reconstitution
Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
Warning
Toxicity: Harmful (C)
This product has met the following criteria to qualify for the following awards: