Biochem/physiol Actions

Reversible: no

Primary Targetα-subunit of G-proteins

Product does not compete with ATP.

Cell permeable: yes

General description

A cell-permeable, amphiphilic, mastoparan analog with five-fold greater potency than Mastoparan Cat. No. 444898. An activator of α-subunit of G-proteins. Evokes rapid upregulation of FAK tyrosine phosphorylation via activation of G-proteins.

Mastoparan analog with five-fold greater potency than mastoparan. An activator of the α-subunit of G -proteins. Evokes a rapid upregulation of FAK tyrosine phosphorylation via activation of G-proteins.

Legal Information

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Other Notes

Mironov, S.L., and Richter, D.W. 2000. Brain Res.853, 60.Park, H.S., et al. 2000. Biochim. Biophys. Acta1484, 151.Zhang, C., et al. 1996. FEBS Lett. 386, 185.Leyte, A., et al. 1992. EMBO J.11 4795.Higashijima, T., et al. 1990. J. Biol. Chem.265, 14176.

Packaging

1 mg in Plastic ampoule

Yes

Physical form

Supplied as a trifluoroacetate salt.

Reconstitution

Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 6 months at -20°C.

Sequence

H-Ile-Asn-Leu-Lys-Ala-Leu-Ala-Ala-Leu-Ala-Lys-Ala-Leu-Leu-NH₂

Warning

Toxicity: Standard Handling (A)