LORLATINIB

Code: PZ0039-25MG D2-231

Biochem/physiol Actions

Lorlatinib (PF-06463922) is a potent, selective brain-penetrable inhibitor of both anaplastic lymphoma kinase (ALK) and c-ros Oncogene 1 (ROS1) with s...


read more

Your Price
€448.25 25MG
€551.35 inc. VAT
REQUEST

Biochem/physiol Actions

Lorlatinib (PF-06463922) is a potent, selective brain-penetrable inhibitor of both anaplastic lymphoma kinase (ALK) and c-ros Oncogene 1 (ROS1) with strong activity against most known ALK and ROS1 mutants identified in patients with crizotinib-resistant disease. It is in clinical trials for the treatment of non–small cell lung cancer (NSCLC).

Legal Information

Pfizer is a registered trademark of Pfizer, Inc.

Sold for research purposes under agreement from Pfizer Inc.

assay≥98% (HPLC)
colorwhite to beige
formpowder
manufacturer/tradenamePfizer®
optical activity[α]/D -95 to -115°, c = 0.5 in methanol
originatorPfizer
SMILES stringNC1=C(O[C@@H](C2=C3C=CC(F)=C2)C)C=C(C4=C(C#N)N(C)N=C4CN(C)C3=O)C=N1
solubilityDMSO: 2 mg/mL, clear
storage temp.room temp
Code
Description
Unit Size
List Price
Qty
PZ0039-5MG
LORLATINIB

Unit:5MG
List Price: €108.70
Source:List Price
ADD
This product has met the following criteria: