L-742001

Code: SML1010-25MG D2-231

Biochem/physiol Actions

L-742,001 is an inhibitor of the influenza virus RNA polymerase PA subunit, implicated in several roles, including endonuclease and protease activitie...


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€430.70 25MG
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Biochem/physiol Actions

L-742,001 is an inhibitor of the influenza virus RNA polymerase PA subunit, implicated in several roles, including endonuclease and protease activities as well as viral RNA/complementary RNA promoter binding. L-742,001 inhibits the influenza endonuclease-dependent polymerase activity with an IC50 of 430 nM.

L-742001 is useful in the treatment of influenza viral infection.

assay≥98% (HPLC)
colorwhite to beige
formpowder
InChI keyLMLNSXCRZNNZBT-VSOKSMTPSA-N
InChI1S/C23H24ClNO4.ClH/c24-19-8-6-17(7-9-19)15-23(21(27)14-20(26)22(28)29)10-12-25(13-11-23)16-18-4-2-1-3-5-18;/h1-9,14,26H,10-13,15-16H2,(H,28,29);1H/b20-14-;
Quality Level100
SMILES stringO/C(C(O)=O)=CC(C(CC1)(CC2=CC=C(Cl)C=C2)CCN1CC3=CC=CC=C3)=O.Cl
solubilityDMSO: 20 mg/mL, clear
storage conditiondesiccated
storage temp.2-8°C
Cas Number174605-64-2
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