KY-05009

Code: SML1506-25MG D2-231

Biochem/physiol Actions

KY-05009 is a Traf2- and Nck-interacting kinase (TNIK) inhibitor that inhibits the epithelial-to-mesenchymal transition (EMT) in cancer cells.

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€602.50 25MG
€741.08 inc. VAT
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Biochem/physiol Actions

KY-05009 is a Traf2- and Nck-interacting kinase (TNIK) inhibitor that inhibits the epithelial-to-mesenchymal transition (EMT) in cancer cells.

KY-05009 is also known as (5-(4-methylbenzamido)-2-(phenylamino) thiazole-4-carboxamide). It prevents the proliferation induced by interleukin-6 and promotes cell death by blocking Wnt signaling in multiple myeloma (MM) cells. KY-05009 is a novel aminothiazole, which possesses anti-cancer activity in human colorectal cancer cells. KY-05009 prevents migration and invasion stimulated by TGF-β1 (transforming growth factor beta 1).

Packaging

5, 25 mg in glass bottle

assay≥98% (HPLC)
colorlight yellow to dark yellow
formpowder
InChI keyWCEDGRTWDSHZHF-UHFFFAOYSA-N
InChI1S/C18H16N4O2S/c1-11-7-9-12(10-8-11)16(24)22-17-14(15(19)23)21-18(25-17)20-13-5-3-2-4-6-13/h2-10H,1H3,(H2,19,23)(H,20,21)(H,22,24)
Quality Level100
SMILES stringNC(C1=C(NC(C2=CC=C(C)C=C2)=O)SC(NC3=CC=CC=C3)=N1)=O
solubilityDMSO: 10 mg/mL, clear
storage temp.2-8°C
Cas Number1228280-29-2
This product has met the following criteria to qualify for the following awards:



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