Biochem/physiol Actions

Primary Target5-LO

General description

An inhibitor of cytochrome P-450 in steroid biosynthesis. An anti-fungal agent that displays potent anti-metastatic, anti-neoplastic, and anti-psoriatic activities. Also acts as an inhibitor of 5-lipoxygenase (5-LO; IC₅₀ = 26 µM) and thromboxane synthase activities.

An inhibitor of cytochrome P-450 in steroid biosynthesis. An antifungal agent that displays potent anti-metastatic, anti-neoplastic, and anti-psoriatic activities. Also acts as an inhibitor of 5-lipoxygenase (5-LO; IC₅₀ = 26 µM) and thromboxane synthase activities.

Legal Information

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Other Notes

Due to the nature of the Hazardous Materials in this shipment, additional shipping charges may be applied to your order. Certain sizes may be exempt from the additional hazardous materials shipping charges. Please contact your local sales office for more information regarding these charges.

van Wauwe, J.P., and Janssen, P.A.J. 1989. J. Med. Chem. 32, 2231.Beetens, J.R., et al. 1986. Biochem. Pharmacol. 35, 883.Lambert, A., et al. 1986. Biochem. Pharmacol. 35, 3999.Tucker, W.F.G., and MacNeil, S. 1986. Br. Med. J. 293, 882.Lelcuk, S., et al. 1984. J. Trauma 24, 393.

Packaging

50 mg in Glass bottle

Warning

Toxicity: Toxic & Carcinogenic / Teratogenic (G)