KC7F2

Code: SML1043-1MG D2-231

Biochem/physiol Actions

KC7F2 is a cell permeable potent HIF-1 pathway inhibitor. KC7F2 inhibits the activation of HIF-target genes such as carbonic anhydrase IX, matrix meta...


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€50.20 1MG
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Biochem/physiol Actions

KC7F2 is a cell permeable potent HIF-1 pathway inhibitor. KC7F2 inhibits the activation of HIF-target genes such as carbonic anhydrase IX, matrix metalloproteinase 2 (MMP2), enolase 1, and endothelin 1. KC7F2 suppresses the protein accumulation of HIF-1? in cancer cell lines by inhibition of its protein synthesis at the translation level. KC7F2 is preferentially cytotoxicity to cancer cells, an effect that is increased in hypoxia.

Features and Benefits

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Other Notes

air sensitive

Packaging

1, 5 mg in glass bottle

assay≥98% (HPLC)
colorwhite to beige
formpowder
InChI keyREQLACDIZMLXIC-UHFFFAOYSA-N
InChI1S/C16H16Cl4N2O4S4/c17-11-1-3-13(19)15(9-11)29(23,24)21-5-7-27-28-8-6-22-30(25,26)16-10-12(18)2-4-14(16)20/h1-4,9-10,21-22H,5-8H2
Quality Level100
shipped inwet ice
SMILES stringClC1=CC=C(Cl)C=C1S(NCCSSCCNS(C2=C(Cl)C=CC(Cl)=C2)(=O)=O)(=O)=O
solubilityDMSO: 20 mg/mL, clear
storage temp.−20°C
Cas Number927822-86-4
This product has met the following criteria to qualify for the following awards:



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