Biochem/physiol Actions

ISOX-DUAL is a potent dual inhibitor of the bromodomain of CREB binding protein (CBP BRD) and bromodomain-containing protein 4 (BRD4).

Legal Information

Pfizer is a registered trademark of Pfizer, Inc.

Sold for research purposes under agreement from Pfizer Inc.

Other Notes

This compound was developed by Pfizer for Gene Regulation research. To learn more about Sigma′s partnership with Pfizer and view other authentic, high-quality Pfizer compounds, visit sigma.com/bsm-pfizer.

Packaging

5, 25 mg in glass bottle

assay	≥98% (HPLC)
color	white to beige
form	powder
InChI key	HCDQWCDANVEBQR-UHFFFAOYSA-N
InChI	1S/C31H41N5O3/c1-23-31(24(2)39-33-23)26-9-12-29-28(22-26)32-30(36(29)16-15-35-17-20-37-21-18-35)13-8-25-6-10-27(11-7-25)38-19-5-14-34(3)4/h6-7,9-12,22H,5,8,13-21H2,1-4H3
manufacturer/tradename	Pfizer^®
originator	Pfizer
Quality Level	100
SMILES string	CC1=NOC(C)=C1C2=CC(N=C(CCC3=CC=C(OCCCN(C)C)C=C3)N4CCN5CCOCC5)=C4C=C2
solubility	DMSO: 10 mg/mL, clear
storage temp.	room temp

This product has met the following criteria to qualify for the following awards:

ISOX-DUAL

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